Nrf2, encoded by the gene Nfe2l2, is a broadly expressed transcription factor that regulates gene expression in response to reactive oxygen species (ROS) and oxidative stress.It is commonly referred to as a ubiquitous pathway, but this generalization overlooks work indicating that Nrf2 is essentially unexpressed in some neuronal populations.To expl

The last quarter century has heralded dramatic changes in the field of pediatric neuro-oncology, with the era defined by profound developments in the understanding of the biological Bookcase underpinnings of childhood central nervous system (CNS) tumors and translational therapeutics.Although there have been momentous strides forward in biologic, d

In Slings Waiting for Godot (1953) Beckett draws upon a non-temporal stasis that has paralyzed the nation over the past decades, and demystifies such a paralysis by structuring the play around not only a fixed milieu and an unnamable saviour but also a widespread unwillingness in appreciating the urgency of this dominant spirit of stasis.I argue th

One of the aspects that has supported the idea of the azulejo (tile) as a cultural underwear heritage of the Portuguese identity is its continuous employment since the end of the fifteenth century until today, now having become a part of the projects of artists, architects and designers.This article seeks to ponder upon the relationship that contem

Eyaya Habtie Dagnaw,1 RESCUE REMEDY SPRAY NIGHT Fillorenes Ayalew Sisay,1 Selamawit Girma Tadesse,1 Dejen Feleke,2 Getaneh Atikilt Yemata,3 Besfat Berihun Erega,1 Wondminew Gashaw Kettema,4 Mandefro Asfaw Geremew4 1Department of Midwifery, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; 2Department of Pediatrics Health an